First live birth following uterine transplantation from a deceased donor

 

 

Uterine

Medical team hold the first baby born via uterus transplant from a deceased donor at the hospital in Sao Paulo, Brazil December 15, 2017 in this picture handout obtained on December 4, 2018. Hospital das Clinicas da FMUSP/via REUTERS ATTENTION EDITORS – THIS IMAGE HAS BEEN SUPPLIED BY A THIRD PARTY. MANDATORY CREDIT.

Medical journal ‘The Lancet’ has just published an article describing the very first live birth following uterine transplantation from a deceased donor, carried out in São Paulo, Brazil. The transplant recipient was born with Mayer-Rokitansky-Küster-Hauser syndrome, a congenital disorder which prevents development of the uterus.

The patient, who underwent IVF seven months post-transplant, gave birth in December 2017 to a healthy baby girl at 36 weeks of gestation. While uterine transplantation may offer an alternative to surrogacy for women born without a uterus, it is still regarded as an experimental procedure, and remains available only in highly specialized centres.

However, this study marks an important advance for the treatment of congenital uterine infertility.   To read further details please click on the links below:

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)31766-5/fulltext

https://www.theguardian.com/commentisfree/2018/dec/06/live-birth-dead-donor-definition-motherhood-transplants-pregnancy

 

 

 

 

Healthy Eating – Baked Salmon & Mixed Bean Salsa

Healthy Eating

This meal is suitable for the following: healthy eating, weight management, low GI, preconception, endometriosis, PCOS, men’s health. Salmon is a great source of protein and is rich in healthy omega 3 fatty acids and vitamin D. It is also a good source of iron. Mixed beans are a low GI food and a great source of fibre.

FOR 4 :
4 Salmon fillets
1 lemon halved
90g (3oz / 1 bunch) coriander leaves, chopped
ground black pepper

Mixed Bean Salsa:
440g can of mixed beans, rinsed and drained
1 tbsp black olives, chopped
6 sundried tomatoes, chopped
1 red chili, finely chopped
1 small red onion, finely chopped
1 tbsp olive oil
2 tsp balsamic vinegar

Pre heat oven to 180 (350 / GM4). Put salmon fillets in ovenproof dish. Squeeze the lemon over fillets, sprinkle with ½ coriander leaves and season with pepper. Cover with foil and bake for 20 – minutes.

Combine all the ingredients for mixed bean salsa in a bowel. Add remaining coriander and mix well.

Put all ingredients for salad dressing in a screw top jar and shake. Drizzle over salad leaves.

Put cooked salmon fillets on each plate, top with bean salsa and serve with green salad.

For a main meal serve with 150g cooked couscous per person (156kcal)

Nutrition per serving:

Kcal 464 (medium)
Fat 24g (low in unhealthy fat; high in healthy oils)
Carbohydrate 15g (low)
Protein 45g(high)

Nutrition notes:

• Sunblush tomatoes have a milder, sweeter flavour than sundried and make a tangier salsa. Fresh halved cherry tomatoes would also work very well, and all tomatoes are a great source of vitamin C for iron absorption and lycopene- a nutrient that has been shown to reduce men’s risk of prostate
• Mixed beans are a low GI food and a great source of fibre. They are widely available, but you can use a combination of any tinned beans in brine (salted water) you like, or add some sweetcorn for variety
• The dish tastes good cold, so it can all be prepared in advance. The fish could also be cooked on the barbeque
• To vary the flavour, try using lime instead of lemon or flatleaf parsley instead of coriander
• This dish is low in carbohydrate. It works well with baby new potatoes or noodles on the side. A small serving will add about 80kcal and 20g carbohydrate.

UK fertility regulator to issue new rules on expensive IVF add-ons

IVF patients will need to be told when expensive “add-ons” to fertility treatments are not likely to be effective, under new rules due to be issued to clinics later this year.

The crackdown by the government’s fertility regulator, the Human Fertilisation and Embryology Authority, comes as an increasing number of clinics are charging patients top-up fees for experimental procedures that have not been tested in clinical trials, or have been shown to make no difference.

To view the full article please click on this link

Mediterranean Style Diet and IVF

When the sun shines, it can feel like Ireland has moved a little closer to the Med. You may find that you eat more salads and fruit in summertime, and the good news is that as well as being delicious, this change in eating pattern could be beneficial if you are preparing for IVF. A Mediterranean style diet may help to improve IVF success rates for women under 35 years of age who are not obese, a recent study suggests.

Mediterranean Diet

The researchers looked at the eating habits of 244 women undergoing their first IVF treatment at a clinic in Greece during a 3 year period. None of the women included in the study were obese and they were aged between 22 and 41 years old. The women’s diets were rated using a validated scoring tool, and then researchers looked at whether their diet score had any association with the outcome of their IVF treatment.

The MedDietScore (range 0–55) assesses how closely people follow the Mediterranean diet. Eating foods close to a traditional Mediterranean dietary pattern (non-refined cereals, fruits, vegetables, legumes, olive oil, fish and potatoes) are awarded scores 0 to 5 for never, rare, frequent, very frequent, weekly and daily consumption. Foods away from the Mediterranean pattern (red meat and processed meat products, poultry and full fat dairy products) score negatively.
Among women younger than 35 years, a 5-point increase in the MedDietScore was associated with ~2.7 times higher likelihood of achieving clinical pregnancy and live birth. This meant that the women in this study with the highest scores were more than twice as likely to have a baby than those with lowest scores.

It’s important to note that the design of the research means that we can’t predict that the benefits seen by the women in this study would translate to all other women undergoing fertility treatment, or to obese women, and the same results were not seen for women over 35 years. However the researchers suggest that following a Mediterranean style diet may help to increase the chances of a successful pregnancy for women undergoing IVF treatment.

“Adherence to the Mediterranean diet and IVF success rate among non-obese women attempting fertility” Karayianis et al Human Reproduction, Volume 33, Issue 3, 1 March 2018, Pages 494–502

If you would like to make some changes to your own diet, try this simplified version of the Mediterranean diet score. Focus on a few key changes every week to increase your score as part of your overall plan. Include a supplement of 400mcg Folic Acid and at least 10mcg Vitamin D3 from at least 3 months before any treatment.

Diet 1

 

 

Sinéad Curran, dietitian

merrionfertilitydietitian@gmail.com

MFC collaborate with UCD Perinatal Research Centre

The UCD Perinatal Research Centre, based at the National Maternity Hospital, Dublin, coordinates national and international collaborative research in maternal health and its impact on maternal and infant outcomes. Led by Centre Director Professor Fionnuala McAuliffe, the Centre is internationally recognised for its research in maternal and fetal health, diabetes and nutrition in pregnancy and the impact of maternal health on long-term health of Mum and infant.

The Centre is having its official launch on Thursday 15th March 2018 and we are delighted to announce that Merrion Fertility Clinic have collaborated with the centre on research in the area of reproductive medicine on their website.

http://www.ucd.ie/medicine/perinatal/reproductivemedicine/

Click on the following link for more information on Merrion Fertility Clinic’s research studies.

 

 

 

 

 

Prof. Wingfield speaks at the Oireachtas

Prof. Mary Wingfield spoke at a meeting at the Oireachtas on the 28th February 2018 regarding the proposed Assisted Human Reproduction Bill. Dr. John Waterstone and Dr. John Kennedy were also in attendance.

Prof Wingfield was a member of the Commission on Assisted Human Reproduction, which produced its report in 2005, and she is delighted to see that, except for the proposals on parenthood in surrogacy, the draft Bill accords with the recommendations of the Commission.

Click here for her opening statement.

To view the full meeting please click on this video link.

Prof. Mary Wingfield’s interview on ‘The Pat Kenny Show’

Please click on the audio link below to listen to Professor Mary Wingfield’s interesting discussion on everything fertility with Pat Kenny on Newstalk, she also answers some of the listeners’ questions.

If you wish to make an appointment at Merrion Fertility Clinic to check your fertility status and to have a consultation with one of our fertility doctors’, please phone us on 01 6635000 or complete our online self-referral form.

For more information on Prof. Wingfield’s book please visit ‘The Fertility Handbook’.

Only Constitutional Right of Unborn Is Right To Life

The Supreme Court has unanimously ruled that the unborn has no constitutional rights outside the right to life inthe Eighth Amendment.

In a landmark judgment on Wednesday, the seven-judge court ruled that the High Court was wrong to find the unborn has constitutional rights outside Article 40.3.3 and was also wrong to find the unborn is a child within the meaning of Article 42a.

For the full article please click on the following link